UroToday.com - This be a life-size case-control den estimate prostate cancer amount among user of statins and other cholesterol-lowering drugs contained by a study population of 24,723 case-control pairs. It is a register-based study with all not long diagnose prostate cancer cases in Finland during 1995-2002 and one next to one matched controls. The figures resistant medication bring to take on sheet have be obtain from a prescription database providing detailed information all for both man in the study population.
Based on their article of buying, the researchers offer that early sleep problems may be resolute as a "marker" for envisage following hazard of early adolescent substance use -- and that within may be a undivided unprocessed factor underlying both traits. The empathy between sleep problems and the use and verbal abuse of alcohol in adults be capably structured, but this is the opening study to face at the dynamic in family.
These finding be in concordance with the most up-to-date grades on this pasture. However, this is the opening study to comprehensively match able to the risk in users of other cholesterol-lowering drugs additionally in place of individual statins.
Study strengths contain large study population and detailed information on medication use allowing analyses of prostate cancer risk according to circumstance and dosage of the use. The major destitute principle is the not good enough information on serum PSA carrying out tests. Thus, confounding wreak by opportunistic PSA testing among the study population could not be controlled for. However, the illustrious proportion of opportunistic PSA screening in the Finnish population is reportedly thin (less than 20%), albeit escalating. In the approaching these results enjoy need of to be confirmed by a study controlling for the effect of PSA testing.
Written by Murtola TJ, MD, as portion of Beyond the Abstract on UroToday.com. This initiative offer a tactic of publish for the office urology colony. Authors are given an opportunity to raise vigilant on the surroundings, limitations etc... of their research by referencing the published abstract.
"Reprinted with authorization from You can viewpoint the inclusive Kaiser Daily Health Policy Report, manifestation into the archives, or see conscious for email confinement at /dailyreports/healthpolicy.
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