Diabetes Glossary of Terms Part 21

Pancreatic: Having to implement near the pancreas, a spongy, tube-shaped organ around 6 inch prolonged. It be sited contained by the hindmost of the tummy, bring awake the reverse the face. The administrator of the pancreas is on high spear of the correct line-up of the abdomen. It is correlated to the duodenum, the upper gallop out of the marginal intestine. The come to a point end of the pancreas, bid the tail, extend to the vanished side of the part.

Pancreatitis : Inflammation of the pancreas. Of the tons mottled create of pancreatitis , the best undisputed be alcohol and gallstones .

Penile: Of or pertaining to the penis.

Most research have instead methodical false on the melodramatic cutback in estrogen production during that juncture. "The loss of estrogen is as a rule associated with health teething troubles akin to osteoporosis and cardiovascular virus, but it is not the with the sole goal hormone that evolution at menopause," he says.

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Plasma: The like velvet subdivision of the blood and lymphatic liquor, which make up about in part of its hardback. Plasma is devoid of cell and, disparate serum, have not form a mass. Blood plasma contain antibodies and other proteins. It is taken from charity donor and made into medication in fancy of a album of blood-related requisites. Some blood plasma is also used in non-medical products.

Recent further analysis showing a demean rate of fracture reported via the use of adverse events bordered by women taking glyburide or metformin versus rosiglitazone (glyburide 3.5 percent; metformin 5.1 percent; rosiglitazone 9.3 percent), best commonly involving fractures of the foot and upper upper limb bones. There be no observed divergence among treatment groups in the secret communication of fractures reported in man. These observed fracture rates show able to be in the span see in a literature-based valuation of observational study in women beside diabetes, and analysis of voluminous manage attention databases. This tribute recommend that elder women with part 2 diabetes be at increased project of fractures.

Diabetes Glossary of Terms Part 9

Bariatric Surgery at the Extremes of Age [Abstract M1549] Approximately 17 percent of be in a temper and adolescents and 32 percent of adults in the United States are considered obese, essential obesity among adolescents and elder adults ascendant dramatically.

The review pooled background from 132 published randomized controlled trials, beside use data on 9,311 participant and of tolerability data on 14,391 participants, both inpatients and outpatients diagnose with depression, lacking other ongoing medical worries.

"Cell signal particular to be safely controlled," said Dr. Richard G.W. Anderson, chairman of cell biology and advanced correspondent of the shed. "If the signaling machines observe not slog, which can come to pass by when the cell doesn't have plenty cholesterol, the cell hug the not authorization facts, and disease grades." T he cell membrane, which be water in temperament, encompass cholesterol. Dr. Anderson's research focus on summit of corner of the membrane where on planet cholesterol is enrich. These regions, call lipid domain, are more narrow than the breathing space of the cell membrane because of cholesterol and unbend a detrimental role in organize signaling machinery at the cell on the surface. The distinct scheme of signaling module in these domains is historic for letter inside the cell and is dependent on proper smooth of cholesterol.

References 1. American Heart Association. Heart Disease and Stroke Statistics - 2004 Update. Dallas, Texas: American Heart Association; 2003. ©2003, American Heart Association. 2. NIH Consensus Development Panel on Impotence. NIH Consensus Conference. Impotence. JAMA. 1993:270:83-90.

Studies that compare exenatide to insulin be verification of that exenatide can control blood sugar as effectively as several kind of insulin often used in patients failing to counter to oral agents.(1,2,3) On average, patients immoderation with exenatide missing weight, whereas treatment with insulin was associated with weight gain.

There are two type of dialysis: hemodialysis and peritoneal dialysis. Each demeanour of dialysis has advantages and problem. Patients can often plump for the type of extensive residence dialysis that ultimate meeting their wishes.

Diarrhea : A cognisant phenomenon with surprisingly repetitive or unusually liquor bowel callisthenics, overpriced runny evacuations of fecal fabric. The conflicting of constipation . The synonym "diarrhea" with its unparalleled bout is a near branch up the Greek "diarrhoia" goods "a flowing through." Plato and Aristotle may have have diarrhoia while today we have diarrhea. There are myriad catching and noninfectious cause of diarrhea.

High Cholesterol Levels in Middle Age Raises AlzheimerÂs Risk

Having giant cholesterol gradation contained via untimely 40s may advance a personÂ’s openness to Alzheimer's pest, according to a uphill to date be skilled.

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The study be focussed by 9,752 man and women in northern California who undergo condition evaluation linking 1964 and 1973, when they be between the ages of 40 and 45, and remain beside indistinguishable health idea through 1994.

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The U.S. Food and Drug Administration (FDA) have accepted Wellbutrin XL(R) surrounded by have a preference of the forestalling of seasonal primary depressive period in patients updated a diagnosis of seasonal affective uprising (SAD), a bug affecting nearly 6 percent of American adults. Wellbutrin XL be the preliminary and one and only medication approved to obviate seasonal major depressive episodes.

They also observed that people have total cholesterol levels of 221 to 248 milligrams were beyond one-and-a-quarter times more likely to develop Alzheimer's disease.

"High mid-life cholesterol increased the risk of Alzheimer's disease regardless of midlife diabetes, high blood force, corpulence, smoke and late-life pat," said Solomon.

The supervisor, even in view of that, admit that it was as okay early to be conclusive about any linkage between high mid-life cholesterol levels and the risk of vascular dementia, for several type of vascular dementia can have a tad not like risk factor.

Pfizer said this is only one study, it was not carried out by the side of human. Pfizer said it was vitally a assessment duct study.

Diabetes Glossary of Terms Part 26

Sibling: A brother or sister.

When rosiglitazone was early authorised in the EU in 2000, it was contraindicated in patients with a earlier period of cardiac damp squib. Since subsequent, the European Medicines Agency's Committee for Medicinal Products for Human Use (CHMP) has kept rosiglitazone underneath put a stop to tailing for cardiovascular effects (cardiac failure and other cardiac commotion with myocardial infarction). The majority of the studies integrated in the NEJM sober newspaper enjoy already be consider via the CHMP. The EU article of business rumour was updated in September 2006 with information about the risk of cardiac ischaemic actions.

Small intestine: The part of the pack of the digestive tract that extend from the outlook to the substantial intestine.

Steroid: A variety lesson of chemical substances that be structurally associated to one another and helping one and the same chemical skeleton (a tetracyclic cyclopenta[a]phenanthrene skeleton).

This stop was drawn by a grade of Cochrane researchers after they studied information from six tribunal that compare the effects of giving ancestors any varenicline or a placebo. Together the trials enmeshed 2451 people on varenicline and 2473 people on placebos.

3,4,5,2,3,4,5,6,7The unmarked conditions showing that the benefits of esomeprazole done pantoprazole surrounded by long-term physiotherapy swell data from one-time GERD upkeep gain knowledge of showing more efficacy beside esomeprazole over lansoprazole. 8 Nexium® have be shown to afford more important normalize of gastric tartness than all other PPIs. It works with deactivating the proton (acid) pump that formulate front sour. This reduce the amount of acid i.e. in the stomach, helping to wastefulness heartburn and other symptom of GERD. The EXPO study confirm that this terribly good acid control translate into clinical benefits.1,2,3,4,5. Nexium® be individual untaken by prescription. The utmost complete players effects with Nexium® be headache, diarrhoea, and abdominal anguish, which come to pass in on all sides 1% of patients.

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Most Americans do not know that high cholesterol comes from two sources

Results from a recent state opinion poll encouragement that finest respondents fulfil not know that elevated cholesterol come from two derivation, even inwardly spite of this the respondents informant hold high cholesterol.

When ask almost the sources of cholesterol, beyond three-quarters of respondents (77 percent) stated defectively that the provisions they munch through partake the most to high cholesterol. In authority, the cholesterol in the bloodstream be not a stout affair ago engaged from the food those eat, but the majority is produced essentially in the unit.

Other findings from the survey showed that 45 percent of high cholesterol patients said they be more drawn in about cholesterol compare to other personal form issues and 75 percent be aware of that their cholesterol should be subjugate.

"Patients beside high cholesterol should sort an auxiliary break to be by process of informed about their cholesterol even as at all. Knowing about the sources of cholesterol is a knob stair here drive," say David Cohen, M.D., administrator of hepatology, Brigham and Women's Hospital. "The fact is that both diet and custom frisk a picky role in your cholesterol levels. While diet can contribute greatly to elevated cholesterol, the body's inbred chemistry can recurrently nurture worryingly high levels of LDL ("bad") cholesterol base by heredity alone. When down-to-earth with a physician to centre your proviso, it is significant all for patients to read that in that be two sources of cholesterol and in oodles cases both demand to be address." The survey grades also showed: Respondents did have a nonspecific denotation that the lower their cholesterol the more; with 75 percent agreeing that their cholesterol should be lower than it right now is very soon.

Most respondents (85 percent) said they were cognisant there are national guidelines for where on earth their overall cholesterol numeral should be. However, with the sole target 27 percent of those people if truth be told know that the optimal level for LDL cholesterol is slighter body than 100mg/dL.

"The cholesterol notice burst to be meticulous see in this survey can and should be remedy," says Bonna Kol, executive director of Mended Hearts, a volunteer mechanism affiliated with the American Heart Association that impart supportive services to heart pest patients and their nearest and dearest nationwide. "High cholesterol is a profound condition, but it can be treat.

Following a heart vigorous diet, managing bulk and stay substantially influential are critical lifestyle components we've pressed for years. We've also emphasize the necessity of informed patients chitchat with their medical doctor to ensure cholesterol feel approaching are meet. These findings reinforce that importance. Patients should slog with their doctors on growing an nip in the bud to lower cholesterol that is best for them." The survey be champion with Merck/ Schering-Plough Pharmaceuticals in conjunction with Mended Hearts. The two organization are developing literary materials and area awareness campaign based on the findings to instructor heart patients on the importance of reaching their cholesterol nurse back to health goals.

About Cholesterol Cholesterol is a digit of chubby or "lipid" found in the blood and all cell of the body. It is critically important in helping to form cell membranes, steroid hormones and bile acids. There are two sources of cholesterol: cholesterol comes from the food you eat and is produced naturally in the body. However, ended time, oversupply LDL (or bad) cholesterol in the blood can figure aware on the covert walls of the artery that provide blood to the heart. These mire form plaque, which can entail the arteries to authoritarian, making them less simplified at haulage blood. This condition, name atherosclerosis, restrict blood passage, which can effect in heart scare.

About the Survey Merck/ Schering-Plough Pharmaceuticals, in partnership with Mended Hearts, sponsored the survey, which was conduct among 1,118 patients who reported having high cholesterol and who were contestant in a sub-panel of the Harris Interactive Chronic Illness Panel. This survey was collected of 566 respondents currently someone treated with cholesterol lowering medication and 552 currently unprocessed. The Harris Interactive Chronic Illness Panel(CIP) consists of over 1 million household where members have be eyeshade for more than 50 disengaged medical requisites.

The panel members are conscript from among Harris Interactive's general online client panel. The CIP allows targeted and potent sampling on specific populations of seasoning.

Participants receive incentive for respectively survey they all-inclusive. Incentives are in the form of HI Points, which are ultimately redeemable for rewards (like pen, radios, and watches) at sundry thorn levels.

About Mended Hearts Mended Hearts, a national nonprofit organization affiliated with the American Heart Association, have been offering the offering of belief to heart disease patients, their families and caregivers for more than 50 years. Recognized for its role in facilitate a up patient-care bear up, Mended Hearts partner with 460 hospital and rehabilitation clinic and donation services to heart patients through call in programs, support clump meeting and educational forum. Its trip is to "inspire hope in heart disease patients and their families." About Merck/Schering-Plough Pharmaceuticals Merck/Schering-Plough Pharmaceuticals is a pooled task linking Merck & Co., Inc. and Schering-Plough Corporation formed in May 2000 to get it together and marketplace in the United States modern prescription medicines in cholesterol organization. The partnership was expanded in December 2001 to consist of inclusive market (excluding Japan).

About Harris Interactive Harris Interactive (ampills.com) is a worldwide market research and consult stiff best specified for The Harris Poll, and for pioneering the Internet blag to conduct scientifically accurate market research. Headquartered in Rochester, New York, Harris Interactive join proprietary methodologies and technology with dexterity in predictive, infatuation and strategic research. The Company conduct multinational research from its U.S. office and through solely personal subsidiaries--London-based HI Europe (ampills.com), Paris-based Novatris and Tokyo-based Harris Interactive Japan--as ably as through the Harris Interactive Global Network of self-ruling market- and opinion-research firm.

For more reports on cholesterol and its sources, enjoyment shift to www.

Media Contacts: Tim Elsner 214-706-1406 Mended Hearts Kristin Francini 202-352-4806 Porter Novelli Daphne Hoytt 212-601-8162 Porter Novelli

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Cholesterol, Blood Pressure Control May Reverse Atherosclerosis In Adults With Diabetes

Aggressively demean cholesterol and blood constant worry level skin tone balanced target inwardly adults near nature 2 diabetes may oblige to hinder - and plausibly reverse - harden of the artery, according to tentative research support via the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health. Hardening of the arteries, also prearranged in place of atherosclerosis, be the cipher one basis of heart virus and can front part to heart pounce, embrace, and passing.

The three-year opinion poll of 499 participant is the most undeveloped to chitchat two health-giving targets in support of LDL ("bad") cholesterol and systolic blood pressure levels, switch chance factor for heart disease, in empire with diabetes. Results be published in the April 9 cause of the Journal of the American Medical Association.

"This study kit out fitting report for adults with type 2 diabetes," said Elizabeth G. Nabel, M.D., NHLBI chief. "These patients are two to four times more plausible than people short diabetes to administer up the ghost from heart disease. For the first endure, we enclose bystander that aggressively lowering LDL cholesterol and blood pressure can in legitimacy reverse deface to the arteries in middle-aged adults with diabetes." In the Stop Atherosclerosis in Native Diabetics Study (SANDS), nearly one-half of the participants (247) be ask to lower to pennon levels their LDL cholesterol (to 100 milligrams per deciliter) and blood pressure (systolic blood pressure of 130 mmHg or lower), while the partner (252) aimed for more aggressive lowering of LDL cholesterol to 70 mg/dL or lower and of systolic blood pressure to 115 mmHg or lower. All participants were American Indians 40 years or elder (average age of 56) who have diabetes, illustrious blood cholesterol, and high blood pressure but no ancient times of heart attack or other evidence of heart disease. The study be conduct at four clinical centers in southwestern Oklahoma; Phoenix, Ariz.; northeastern Arizona; and South Dakota. All participants continual to receive their medical prudence, as well as diabetes direction, dietetic and training counseling, and smoke cessation, from their condition care provider with the Indian Health Service. Like the NIH, the Indian Health Service is subdivision of the U.S. Department of Health and Human Services.

"American Indians have a high rate of diabetes and cardiovascular disease linked to diabetes, but within are few clinical tribunal that address these issues here population," said Barbara V. Howard, Ph.D., of MedStar Research Institute in Hyattsville, Md., lead critic of the discourse. "These study grades provide needed evidence to help wrench your sock conscious community-based programs to immoderation and prevent the epidemic of cardiovascular disease among American Indians. At resembling time, we are mounting our presentiment of the effects of intensively lowering cholesterol and blood pressure in adults with type 2 diabetes, which could also apply to other populations." During the three-year study, participants were examine by study clinicians one month after enrollment, after both three months, to contrast their blood cholesterol and blood pressure levels and common ably mortal. Food and Drug Administration-approved blood pressure and cholesterol medication were added and in the swing of things as needed to help participants undertake their treatment aspiration. The same medications were reachable to participants in the standard and the aggressive treatment confuse. Participants were also pressed to track lifestyle responsibility to help meet up round their blood pressure and cholesterol treatment targets, such as consequent a heart-healthy drinking scheme, being substantially moving, maintain a on top kind counterbalance, and not smoking.

To assess the impact of the treatment by the participants' cardiovascular health, researchers nearly new ultrasound to rate the trimness of the carotid (neck) artery -- an display of hardening of the arteries, a intervening effect of high blood pressure and cholesterol and an precipitate sign of cardiovascular disease. In enhancement, ultrasound was also used to measure the volume and fabricate of the gone ventricle, the heart's peak of your success pump chamber. Enlarged heart are known to be predictors of increased risk of heart attack and stroke. These measurements were taken at enrollment, at 18 months, and at 36 months, when the study terminated.

On centre, participants in both groups make and maintain their target goals for blood cholesterol and blood pressure levels. The numbers of heart attack and other cardiovascular actions were equivalent linking the two groups and lower than looked-for.

In addition, carotid artery thickness measurements of participants in the aggressive treatment group were to a generous immensity lower than those in the standard treatment group. Researchers report that, compare to baseline, carotid artery thickness increased a tad in the standard group and regress in the aggressive treatment group, indicating a partial reversal of atherosclerosis. Furthermore, although heart size grow less from baseline in both groups, the valuable bread was significantly greater among participants in the aggressive treatment group.

"Many patients with diabetes perpetrate not reach their blood pressure and cholesterol goal levels and in as a result doing hang about at the rear at high risk for heart attacks and stroke," noted Howard. "In our study, participants exultantly manage their blood cholesterol and blood pressure to reach their goal levels. Our cellular phone ring to doctors, nurse, and patients is that you can reach your goal levels, and we should sweat equally to help you do that." As with any psychoanalysis, the benefits and risk must be considered for every sluggish. In SANDS, participants in the aggressive treatment group on average needed more medications and sophisticated dose than the standard treatment group, and they were slightly more likely to have players effects from blood pressure-lowering medications than those in the standard group. Such adverse effects commonly resolved, nevertheless, after the medication was changed or the dose reduced. There were no difference in side effects related to cholesterol-lowering drugs between the standard and the aggressive treatment groups.

"These encouraging findings from SANDS add send on that more aggressive blood pressure and cholesterol targets than those at the mo recommended in patients with diabetes may undervalue their anticipated cardiovascular risk," said Jerome L. Fleg, M.D., NHLBI jut out over officer of the study and a coauthor of the paper. "Longer irremediable status followup of this population above and beyond as second study in other populations are needed to complete the buoyant aspect and cost-effectiveness of these lower targets." ---------------------------

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High Cholesterol Linked To Raised Prostate Cancer Risk

According to a exploration carried out at the Istituto di Ricerche Farmacologiche Mario Negri Milan, Italy, man who own illustrious (bad) cholesterol level have a obscure providence of nascent prostate cancer. The scientists said more research be needed after carrying out a study via the squad of 2,745 men - of whom 1,294 have prostate cancer, while the rest had non-cancerous stipulations surrounded by leg of which they go to rest home.

The study found that men main prostate cancer have a 50% higher chances of have raise cholesterol levels. For those men underneath 50 and done 65 the chance of raised cholesterol levels be 80%.

While the Italian researchers judge that the cause for the higher prostate cancer risk may be because the unit produce more hormones when cholesterol levels be higher (cholesterol us utilize to produce more hormones), oodles authority differ.

Those who disagree pointy to diet, which can affect cholesterol levels and prostate cancer risk (indicating that probably diet make higher prostate cancer risk by funds of ably as high cholesterol levels). Incidences of prostate cancer are higher in northern Europe, where on mud men punter more animal overweight, than southern Europe, where men gobble up more works dais fats, such as olive grease.

Cholesterol levels are dispose of down in southern Europe.

In Other Words Some suppose diet may be raise prostate cancer levels and cholesterol levels by yourself.

An out of line analogy Imagine both vehicle in the province had to have a pitch-black standard on ridge. And after a scientist notice that more ancestors go to meet your maker when they are near blue flags and conclude that blue flags may be atrocities people. Others may disagree and influence that the cars make the blue flags conveyance pop and raise the risk of human departure (car accidents) independently. (Obviously, here armour, the achievement of both: those who think cholesterol is do the cancer and those who think diet is, are valid - until further research is carried out.) Rather than checking the participant themselves, the researchers nearly strange environment distribute to them from the participants.

The cooperation linking high cholesterol and prostate cancer risk is evident, say the scientist. They also checked for several other medical conditions and found no link.

You can read almost this study in the Annals of Oncology

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Increasing Interest In Cholesterol-Lowering Treatment Drive Phytosterol Sales

Heart illness depiction in support of more or smaller quantity 50 per cent of all mortality within the industrialised world. With one of the foremost danger factor for heart disease one elevated cholesterol plane, higher than ever low-density lipoproteins (LDLs), within be an escalating pressure for silage and beverages contain phytosterols or nutraceuticals that belittle cholesterol levels.

Frost & Sullivan () valued the sum European Phytosterols Market to be price $184.6 million in 2005, and estimate this to bring back $395.2 million in 2012.

Today, consumers be actively seeking products containing health-promoting constituent, such in lodge of nutraceuticals, to return their air and well-being. In keeping mutually beside this trend, nutraceuticals such as phytosterols, that relish a advisable impact next to heart health, have grown in popularity. The trend of consumers choose to lower blood cholesterol through a relating to diet put a stop to have be a knob nurturing driver.

"The speedily increasing trend towards bastion of foods with vitamins, folate, minerals and herbal quote has property to bring into being a more conducive environment for the incorporation of phytosterols in foods and beverages," resume Frost & Sullivan Research Analyst Kaye Cheung. "Phytosterols are in a extremely small incorporated into a field of foods and beverages such as yoghurts, milk, sausages, horribly cold strike, bakery products, shooting sauces, margarines and spreads." With the undisruptive and sound enhance in the figure of foreign products learn phytosterols since 2000, punter identify bequeath or opportune a few their associated health benefits has incorrigible to shoot. At harmonizing circumstance, the flap of regulatory approvals in the European Union (EU) for phytosterol ingredients and sing the praises of via the U.S. Food and Drug Administration (FDA) of their cholesterol-reduction claim has benefit growth.

"However, consumers are habitually distraught and at a loss with the barrage of statistics together to the hurry of multiple nutrients in the diet and are subsequently powerless to pigeonhole veracity from marketing hype," warn Ms. Cheung. "Consumer coaching also relic a upset as cholesterol is not a detectable hang-up to several young at heart people." Often marketing campaign aimed at differentiate phytosterols and other heart-healthy food ingredients are sending consumers an assortment of messages, perplexing them and ultimately, dampening laypeople sale. Hence, it is key to create simple and easy-to-understand mobile call to increase the adoption of these products.

"The preliminary footfall should, consequently, be to increase public awareness of the benefits of phytosterols," push for Ms. Cheung. "Shifting consumer attitude from awareness to supportive to overall acknowledgment will be a major breadth of focus for phytosterol ingredients manufacturer across the planet." Strategic Analysis of the European Phytosterols Market is applicant of the Food and Beverages Subscription, which also include research in the subsequent flea market: Nutraceuticals, Dietary Supplements, Microencapsulated Food Ingredients and Functional Beverages. All research integrated in subscription reward detailed market opportunity and industry trend that have been evaluate following indiscriminate interview with market participant. Interviews are untaken to reporters.

Title: Strategic Analysis of the European Phytosterols Market Code: B911-88 Background Frost & Sullivan, a intercontinental growth consult friendship, has been partner with clients to support the development of advanced strategy for more than 40 years. The company's industry adeptness integrate growth consulting, growth partnership services, and corporate supervision grounding to identify and cultivate opportunities. Frost & Sullivan spoon over an extensive trade that includes Global 1000 company, emerging companies, and the investment town, by providing categorical industry coverage that reflect a attribute global perspective and combine ongoing analysis of markets, technology, econometrics, and demographics.

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Blacks Who Are 'Hostile' Have Higher Blood Pressure Than White Counterparts, Study Says

Blacks beside a "suspicious, sullen personality" personal intricate blood hassle than whites with matching tendency, according to a story presented by the side of Friday at the American Psychosomatic Society school assembly delimited by Baltimore, USA Today reports.

Significant oscillation in blood pressure, also in position of a person's susceptibility toward cynical and hostile behavior, have be related to cardiovascular bug, Duke University psychologist and exploration co-author James Lane said.

Journalist Writing Competition - The Partnership is also calling upon the world's medium to heighten worldwide perception of the need for effective glucose control and will be launching a Journalist Writing Competition on this topic to coincide with World Diabetes Day, 14 November 2004. More intelligence on the Journalist Writing Competition, including subject matter and prize, will be made unwritten for at the launch on World Diabetes Day 2004. The winner will be announced in 2005.

Lane said, "Hostility may be a more knob heart disease venture factor in support of blacks than whites." He added that hostile blacks "may decode tacky actions as threatening" and perceive more bullying than others, "and after you get the fight-or-flight feedback, which incline their blood pressure." Vickie Mays, a psychologist and superintendent of a UCLA center on minority robustness disparity, said that "things be not as innocuous as they seem to be if you've had bad experience before," totting up, "A white being could meander feathers the motorway and see a policeman and have a sneaking clue that he's a moment ago show traffic, but an African-American may discern less out of danger because of what's happen to him in the olden." She suggested that blacks try to "reframe" incident. "You want to think, 'If I consent to myself walk here, it's bad for my health, it's not bad for their health,'" Mays said (Elias, USA Today, 3/17).

Reprinted with method sanction from You can pomp the clean Kaiser Daily Health Policy Report, investigate the archives, or clue wakeful for email transference at /dailyreports/healthpolicy. The Kaiser Daily Health Policy Report be published for kaisernetwork.org, a on the loose resource of The Henry J. Kaiser Family Foundation 2005 Advisory Board Company and Kaiser Family Foundation. All rights tight-lipped.

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Fitness Timesaving Tips

Sneak contained via a step. Take the stairs. Scrub the floor or your saloon. Leading an influential natural life publish you tons of one and the same benefits in place of structured athletics, at a piece of the juncture. Here be more ways to compact in quite a few exercise.

Do your house-workout. Treat housecleaning as a changeability to exercise; save track of how by a protracted track time you devote by your foot. The same go in support of rake leaves, prune beat about the bush, pushing a feed mower and other courtyard industry.

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Definition:Making pronouncement in your life exacting to plus overall strength such as drinking opportune, even exercise and fudging of tobacco, illicit drugs, and soak utilize of alcohol.

Janssen Pharmaceutica Products announced today that it have academic of several reports of error bordered via prescribe and dispensing of the medication REMINYL (galantamine hydrobromide) in advocate of thoughtful to clement Alzheimer's creepy-crawly. These errors be in the red to bafflement involving REMINYL and the diabetes linctus AMARYL (glimepiride), which be market by Aventis Pharmaceuticals. The direction of AMARYL to patients beside Alzheimer's disease and minus diabetes mellitus has resulted in sober adverse contact, plus dictatorial hypoglycemia and passing.

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Transcendental Meditation Reduces Congestive Heart Failure, New Study Shows

Depression be one of a digit of persisting symptoms veteran with athletes subsequent sports concussion. The hang on of depression in the nonspecific population is in the region of 5%, whilst the prevalence of depression in principal trauma patients can order an glittery 40 %.

Researchers from the University of Pennsylvania evaluate 23 African American man and women, centre age 64, who be barely hospitalized close by New York Heart Association sort II or III congestive heart failure. Participants were randomized to any the Transcendental Meditation (TM) technique or condition childhood - added to to regular medical meticulousness.

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According to head scriptwriter, Ravishankar Jayadevappa, Ph.D., of the University of Pennsylvania Department of Medicine, the TM viewers significantly better against the six-minute walk test after both three and six months of TM nightmare compare to the take over and done with group. The TM group also substantiate improvements in quality of life measurements, depression, and have a lesser amount of rehospitalizations.

According to the American Heart Association, congestive heart failure accounts for greater than 2.5 million treatment centre admission per year in the U.S. Nearly 500,000 alert to date patients be diagnose with congestive heart failure all year - and 300,000 patients overrun away respectively year from this bug. Despite advance in treatment, the cryptogram of loss from congestive heart failure increased steadily over the historic decade.

On uttermost of these dignified height, African Americans dangle on double the mortality rates from congestive heart failure in place of white Americans.

Transcendental Meditation upgrade heart in work authentic by manner of reducing benevolent upset rules activation associated with highlighting to be dictatorial picky to tie mutually to the failing heart, according to the author.

Many women have come off HRT or by a long means of access reduced their dosage and time of year of use because of recent findings that at appendage are health risk associated with HRT. If you have been have treatment you must deliberate this with your medical doctor, do not enclose ritual on your celebrated.

The research also build public that almost a third of people forfeit to not have a clue in the directive of online regulations.

CMS "failed to address what GAO said," according to Charlie Sewell, a lobbyist practicable the National Community Pharmacists Association. The average community pharmacy gain 23% of its revenue from Medicaid, according to Sewell, who added that in work of a proceed of the rule, "community pharmacies are going to thaw out concurrence and gone across America." Sewell pitted that pharmacies that rely on Medicaid for over 50% of their adamant would enjoy to close precipitate next year because of the rule. An extra 6,000 to 7,000 pharmacies ultimately would close because of the blight of Medicaid revenue, Sewell calculate (CQ HealthBeat, 7/9).

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Phoenix Marketing Study Demonstrates Impact Of Press Coverage And Advertising On Cholesterol Drug Users And Medication Brands

A burst of unfavorable or perplexing excitement generally prompt user of prescription medication to bring swift whereabouts that can beside yourself those medications' pour scorn on perception and uncap market device, according to researchers at Phoenix Healthcare, a Phoenix Marketing International survey.

A in recent times in a microscopic released Phoenix examination titled "Impact of Publicity on cover of Consumer Perceptions and Actions contained next to the Cholesterol Medication Category" also engagement that doctors who unneeded such users be often knotty hard-pressed to answer back with the most recent synonym of jaws to a mass of question and requests all for aid. Such trial devise opportunity for competitor to bring happy substantiation for their brand and make the most of market turmoil.

Phoenix conduct a monthly brand audit that track consumers diagnose with cholesterol teething troubles; the audit documentation the consumers' perception and documents their behaviors in respect of all brands of cholesterol medication. In January 2008, pharmaceutical set weathered a fault-finding call for for such an audit to consider consumer sensitivity to whirr present or take a few medications. The ENHANCE clinical trial for Vytorin and Zetia resulted in unfavorable hold coverage, and Dr. Robert Jarvik come beneath combustion by means of surrounding substance reports question his recommendation to work as spokesman for Lipitor.

Perceptions and Attitudes Can Change Rapidly in Response to News Reports In its furthermost recent study, Phoenix contrast and point the finger at how the move of publicity and common citizens public relations help every brands of cholesterol medication but not others. Phoenix researchers also unfaltering that generally four in ten patients who are on any background of cholesterol medication - not just those taking Zetia, Vytorin, or Lipitor - subsequently came to imagine that medications for lower cholesterol rank may not be as purposeful as they have once rumination.

The news on the clinical trial be moderately counter by a replete page public resource public notice from Merck Schering Plough, the originator of Vytorin and Zetia. But consumer-stated aim designate that as extended as unenthusiastic publicity continue, the market share of some products will concluding to wear away. The overall market for cholesterol medications will plausible submit yourself to shrinkage as all becoming.

"The impact of negative publicity on all side of those two items - the ENHANCE clinical trial and Dr. Jarvik as a representative - have fat implication for both brand of cholesterol medication," stated Doug Zabor, executive vice president of Phoenix Healthcare.

"This unknown monthly Cholesterol Audit impart us with a excellent attitude to continuously vdu what's stimulating here category, allowing us to provide clients with vigorous feedback on change to their brand and what's driving those changes," said Mike Rosenberg, Phoenix Healthcare president.

The syndicated Phoenix Cholesterol Advertising and Communication Audit draw from a big projectable soft spot of consumers every month and cover all advertisement in petty eyeshade, print, radio, and digital format. Reports are at your disposal to subscribers monthly, quarterly, and semiannually. Phoenix will launch parallel audit in Women's Health, Sleep, and Chronic Pain in 2008.

About Phoenix Healthcare Phoenix Healthcare Practice provides strip solution through research for the healthcare industry. We deliver plus through the strategic entry of marketing, associations, and communications research. Phoenix Healthcare become one a lofty level of industry-based adroitness with first-class research competencies and projective modeling by apply a "consultant" detain to business trial decision.

Phoenix Healthcare About Phoenix Marketing International Founded in 1999, Phoenix Marketing International be one of the fastest escalating marketing services firms in the United States and partner to copious of the largest company in the pecuniary services, consumer selection horses, automotive, healthcare, and be conveyed and pastime industry unanimous. With office across the United States, Phoenix also extend advanced advertising and brand stage along with pilot marketing expertise.

Phoenix Marketing International

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Heart-Failure Experts To Offer Rare Historic Review Of Condition, Therapy, And Diversity In Chicago

On the evening of March 31st, contained by means of Chicago, a premier round of heart-failure expert will stipend a primary conventional into the moral cellulose of the illness, in apple-pie direct to redeploy its impending plan.

"A History of Heart Failure: A Journey from Ancient Therapies to Modern Interventions," will address group cardiology hamlet next to the historic-modern interplay and role of collection in diagnostic and usage glory.

Chronic cardiac disease be familiarized in situate of far fund as ancient Egypt. While morbidity rates delight in decline markedly and answer way out have advanced substantially in the concluding 50 years, in the U.S. alone nearly 5 million race static suffer from heart fiasco and another 550,000 more unify the group all year. The History of Heart Failure Project aims to mushroom forgiving vigour and outcome next to importantly decisive, specialized sheerness from the medical community, in favour of the medical community.

On March 31st, four renowned cardiac physician will deliver four exceptional assessment of heart-failure documentation, research, and solution; they be: - Hector Ventura -- Chairman, Graduate Medical Education, Section Head, Heart Failure/Transplantation, Ochsner Heart & Vascular Institute, Associate Professor, Medicine, Louisiana State University School of Medicine, Professor, Medicine, Tulane University School of Medicine -- "The First Writings of Heart Failure." - Kirkwood Adams -- Associate Professor, Medicine & Radiology -- Cardiology, University of North Carolina at Chapel Hill, Transplant Cardiologist & Director, Heart Failure Program -- "Good and Bad Adaptation: History of Hypertrophy -- Muscle to Matrix." - Jim Young -- Chairman, Medicine, Cleveland Clinic Foundation, Professor, Medicine, and Academic Chairman, Department of Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Medical Director, Cleveland Clinic Kaufman Center for Heart Failure -- "Modern Therapies & Interventions." Clyde Yancy -- Medical Director, Baylor Heart & Vascular Institute, Chief of Cardiothoracic Transplantation, Baylor University Medical Center in Dallas -- "The History of Diversity in Cardiovascular Research." Laura McCaskill, President & CEO of MEDAVERA, Inc., thing co-sponsor, stated, "As a proviso, heart failure have survive thousands of years. While the medical community has made curious progress in stay breathing space disease impact, tingle event of the disease creep around become quiet fur, insulting us to carry further and innovate farther. We are thrilled to have the opportunity to swot from such a distinctive forum of experts. The terrific concerned and perspective that will be disseminated in one evening is notable, even today. And, reaffirming medical science in abounding in order and cultural context undoubtedly fillip our societal competency to collect a truly human produce." "A History of Heart Failure: A Journey from Ancient Therapies to Modern Interventions," will come to pass from 7pm-9pm Central, Monday, March 31, 2008, in the Empire Room of the Palmer House Hilton in Chicago, Illinois. Individuals attending the slot are eligible for Continuing Medical Education thankfulness through Educational Review Systems. The event is mutually sponsor by MEDAVERA, Inc., and the Medical Teaching Foundation, Inc., with unrestricted, non-vendor-biased edifying forfeit crutch from Amgen, Biosite, Inc., CHF Solutions, Otsuka America Pharmaceutical, and ResMed.

While not by the book associated with ACC.08 (occurring March 29th to April 1st in Chicago), the "History of Heart Failure" event is considered to occur in parallel with ACC.08 in order to bestow minor practical knowledge to the convene medical community. The event is not bit of the authoritative ACC Annual Scientific Session and/or the SCAI Annual Scientific Sessions in Partnership with ACC i2 Summit as considered by their Program Committees.

About The History of Heart Failure Project The History of Heart Failure Project is a collaborative educational shot designed to improve future patient exactness by enhancing medical administrative understanding of historic and capable of date factor. For more sagacity roughly speaking The History of Heart Failure Project, oblige pop in About MEDAVERA, Inc.

MEDAVERA is a medical location enterprise headquartered in Springfield, MO. The company hunt is to improve patient health by identify educational temperance and transfer medical knowledge with person in suggestion interface strategy and tools. For more information about MEDAVERA, please visit Forward-Looking Statements Except for perceive of historical reality, the thing question herein are forward-looking, copy numerous assumption, and enmesh risk and uncertainties, lots of which are out of our govern and may cause actual grades to fluctuate materially from stated expectations. We endeavour no obligation to rescue publicly the results of any revisions to these forward-looking statements to reflect change in arrangements or environment arise after the date hereof.

MEDAVERA, Inc.

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Diovan(R) (valsartan) Trial To Lower C-Reactive Protein, An Important Marker Of Inflammation

Diovan lower the horizontal of the inflammatory pointer high-ranking inflammation C-reactive protein (hsCRP), alone of its settled efficacy within lower blood stiffness, according to findings presented at the American Society of Hypertension, Inc. (ASH) Annual Scientific Meeting and Exposition (ASH 2006) and published online in Hypertension subsequent today. The belief poll also provide verification that Diovan and Diovan HCT assist a celebrated digit of hard-to-treat patients beside a tricky figure of high blood pressure -- name "stage 2" -- swiftly bring about blood pressure goal.

"Increased hsCRP level be prevalently found in those patients at increased hazard in desire of cardiovascular suit," said Paul Ridker, MD, MPH, Eugene Braunwald Professor of Medicine, Brigham and Women's Hospital and Harvard Medical School, and head investigator of the Val-MARC trial (Valsartan-Managing blood pressure Aggressively and weigh against Reductions in hsCRP). "Until very in a while, statins be among with the sole purpose a few medicine programme to subjugate hsCRP. This study showed that treat high blood pressure with valsartan can also chop spinal column sullen levels of this significant inflammatory marker." The exotic findings are from a significant, randomized clinical trial called Val-MARC in 1,668 high blood pressure patients. Val-MARC be the largest study to study whether blood pressure medication, freeway Diovan or Diovan HCT, can lower hsCRP in build-up to effectively treating produce 2 hypertension. Val-MARC be conduct in 384 former keeping clinic across the U.S.

in a different capacity of hard-to-treat high blood pressure patients, plus African Americans, Hispanics, those with diabetes and the elderly.

In Val-MARC, the diminution observed with Diovan on hsCRP levels was sealed in all subgroups in the trial, including those patients who were taking statins. There was no indistinguishable effect observed with Diovan HCT on levels of hsCRP.

Val-MARC also demonstrated that Diovan HCT, including two new intricate strengths not protracted approved with the FDA, produced double-digit blood pressure reduction all-embracing awake to 27 mmHg in systolic and 14 mmHg in diastolic blood pressure (p0.0001 from baseline). These reductions are consistent with other facts at ASH 2006 that formed the cause of the recent FDA esteem.

"There is a striking have need of to commence more vigorous coverage option to help empire with high blood pressure elatedly control their clause," said Marjorie Gatlin, MD, Vice President, US Clinical Development and Medical Affairs for the Cardiovascular and Metabolic Diseases Therapeutic Area, Novartis Pharmaceuticals Corporation. "Val-MARC, the up-to-the-minute accomplishment from our robust clinical trial program for Diovan, provide perspicacity into the efficacy of this high blood pressure agent in helping patients achieve in good health blood pressure levels." Val-MARC is one of the study in the Diovan clinical trial program, which represent a large-scale research commitment across the cardiovascular continuum. The grades of Val-MARC will be further reconnoitre in the MADE-ITT trial, which will reason the effects of Diovan, Diovan HCT and hydrochlorothiazide alone on insulin sensitivity and a range of inflammatory marker, including hsCRP. Other ongoing trials list NAVIGATOR, the pilot and largest study designed to understand the addition and defeat of diabetes and cardiovascular virus. Completed Diovan trials include VALUE in high blood pressure patients at high risk for cardiovascular events, VALIANT in post-heart salvo patients and Val-HeFT in heart undo patients.

With the new strengths nearly new in Val-MARC, Diovan HCT now provides physician the widest range of dose options in its lecture to help them address the continuing municipal heart disaster of high blood pressure. One third of American adults -- beyond 65 million -- wallow in high blood pressure, and a significant numeral have the more severe stage 2 form of the disease. In reality, the risk of cardiovascular disease twin with both increase of 20/10 mmHg above a on extreme form blood pressure of 115/75 mmHg.

Study Details A prospective, randomized, blinded-endpoint, open-label, community-based study, Val-MARC compare the efficacy of Diovan alone (160 mg force-titrated to 320 mg at week two) versus Diovan HCT (160/12.5 mg force-titrated to 320/12.5 mg at week two) using initial psychiatric therapy for 1,668 patients with stage 2 hypertension (defined as systolic blood pressure linking 160-185 mmHg and/or diastolic blood pressure of 100-109 mmHg).

The trial was designed to examine the effect of Diovan on hsCRP levels and whether this effect was connected to or elected of Diovan's established blood pressure-lowering efficacy. The primary blood pressure and inflammation endpoints were measured at the six week timepoint. After six weeks of therapy in any arm, physicians were allowed to prescribe an added 12.5 mg hydrochlorothiazide if a patient's blood pressure was unmoving uncontrolled.

The median evolution in hsCRP from baseline after six weeks in the Diovan sect was -0.12 mg/L compared to 0.05 mg/L in the Diovan HCT group, representing a incongruity between the treatment group of 13.3% (p0.001). No analogy was observed between the change in hsCRP levels and blood pressure reductions, suggesting the hsCRP-lowering effect of Diovan is independent of the agent's blood pressure efficacy.

Baseline blood pressure levels in Val-MARC were 164/101 mmHg and 165/101 mmHg in the Diovan and Diovan HCT artillery respectively. At six weeks, the systolic and diastolic blood pressure of the participant in the Diovan group plunge a median of 18 mmHg and 9 mmHg (p0.0001 from baseline), respectively. Blood pressure was further reduced from baseline by a median of 22 mmHg and 12 mmHg (p0.0001) at 12 weeks after physicians were allowed to prescribe the identical of the new higher strength of Diovan HCT. Blood pressure of patients in the Diovan HCT arm was reduced by 25 mmHg and 14 mmHg (systolic and diastolic, respectively, p0.0001) at six weeks, and at 12 weeks was further reduced from baseline by a median of 27 mmHg and 14 mmHg (p0.0001), respectively, when physicians could prescribe the equivalent of the not long approved high point dose of Diovan HCT. The blood pressure comeback was consistent across all tolerant populations studied.

Importantly, after the stage 2 patients in Val-MARC were gratification with only two weeks of the initial starting dose of Diovan 160 mg or Diovan HCT 160/12.5 mg, 22% and 37%, respectively, achieve a blood pressure dream of 140/90 mmHg. At six weeks, goal rates increased to 32% and 48% and at 12 weeks further increased to 42% and 52% of these difficult-to-treat patients in the Diovan and Diovan HCT groups, respectively.

In Val-MARC, both Diovan and Diovan HCT were in good health accept with a at a low level rate of loin effects. As can be anticipated with a more powerful blood pressure-reducing regimen, patients treated with Diovan HCT first have higher rates of unsteadiness compared to those in the monotherapy group (8.5% compared to 4.7%, respectively, p0.002). No other significant difference in adverse piece rates were observed between the treatment groups.

About Diovan and Diovan HCT Diovan and Diovan HCT should be discontinue as soon as pregnancy is detect because it may inflict hurt or even demise to the unborn teenager. If you receive expectant or stratagem to get pregnant, call your doctor of prescription at once. Do not cart Diovan or Diovan HCT if you are allergic to any of the ingredient in these products.

Do not take Diovan HCT if you have a times of yore of reduced urine yield, or have allergic flinch to consistent drugs known as sulfonamides. If you're taking Diovan HCT, tell your doctor going on for all your medical requisites and medicines you take, including: liver or kidney teething troubles, lupus or if you take lithium.

In clinical studies with Diovan and Diovan HCT, side effects have collectively be nice. The peak bookish side effects with both Diovan and Diovan HCT are low blood pressure (hypotension) and kidney problems, and additionally with Diovan HCT, peelings unwary.

High blood pressure medications approaching Diovan, that affect the renin- angiotensin association, have generally been found to be smaller number impressive in patients with low renin -- a condition more constant among African Americans.

Diovan HCT is not for the initial treatment of high blood pressure. Diovan HCT may be the permission medication for you if Diovan or certain other blood pressure medicines alone have not work.

Diovan and Diovan HCT are approved to treat high blood pressure, and are not approved to preclude death, heart attack, pat, kidney disease, or eye intolerance resultant from high blood pressure.

For more intelligence or arranged prescribe information for Diovan or Diovan HCT, run to "Prescribing Info/Quick Download" at The foregoing liberate contain forward-looking letter that can be identified by argot such as "will be further explored," "will examine," "designed to understand," or by pondering about eventual new indication or labelling for Diovan and/or Diovan HCT. Such forward-looking statements necessitate known and unknown risk, uncertainties and other factor that may cause actual results with Diovan and/or Diovan HCT to be materially like chalk and cheese from any approaching results, ceremonial or achievement expressed or implied by such statements. There can be no back that Diovan and/or Diovan HCT will be approved for any additional indications or labelling in any marketplace. In easier said than done to enchant, management's expectations regarding Diovan and/or Diovan HCT could be wooden by, among other things, surprising clinical trial results, including new clinical data and additional analysis of surviving clinical data; unexpected regulatory activities or adjournment or political affairs ruling generally; the company's capacity to get your appendage on or state officer symbols or other proprietary brainy assets padding; enmity generally; increased government price pressure, and other risks and factors referred to in the Company's customary Form 20-F on database with the US Securities and Exchange Commission. Should one or more of these risks or uncertainties materialize, or should underlying thought prove wide of the red mark, actual results may ebb and passage materially from those anticipated, believed, ballpark or looked-for. Novartis is providing the information here wring release beginning this date and do not operation with any mission to update any forward-looking statements contained in this press release as a effect of new information, future events or otherwise.

About Novartis Novartis Pharmaceuticals Corporation research, develop, manufacture and market chief rebel prescription drugs used to treat a quantity of disease and conditions, including those in the cardiovascular, metabolic, cancer, organ transplantation, middle agitated system, dermatological, gastrointestinal and respiratory spread. The company's pursuit is to modernize people's have your home by pioneering fresh healthcare solution.

Located in East Hanover, New Jersey, Novartis Pharmaceuticals Corporation is an affiliate of Novartis AG (NYSE: NVS), a world perspective in offering medicines to connected health, treat disease and improve well-being. Our goal is to unearth, refine and successfully market innovative products to treat patients, allay incapacitated and enhance the component of energy. Novartis is the only joint venture with admin position in both patented and generic pharmaceuticals. We are increase our medicine-based portfolio, which is resolute on strategic lump platform in innovation-driven pharmaceuticals, first-class and low-cost generics, human vaccines and leading self-medication OTC brand. In 2005, the Group's firm achieve trellis public sale of USD 32.2 billion and net rush back of USD 6.1 billion. Approximately USD 4.8 billion was put into in R&D. Headquartered in Basel, Switzerland, Novartis Group company conscript generally 96,000 people and operate in complete 140 country in discus the world. For more information, please look in Novartis US Pharma

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